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Increased Serum Estrogenic Bioactivity in Three Male Newborns With Ambiguous Genitalia: a Potential Consequence of Prenatal Exposure to Environmental Endocrine Disruptors
A 2006 study states that in the past 15 years, anomalies of male sexual differentiation have greatly increased in both wildlife and humans in different parts of the world. Environmental endocrine disruptors have been implicated in the dramatic rise in neonatal ambiguous genitalia with variable rates of severity, such as micropenis, cryptorchidism, and isolated or associated hypospadias.